John DeSpain, MD, FAAD
Board-Certified Dermatologist
5.0 /5
400 reviews

John DeSpain, MD, FAAD

Dr. John DeSpain is a highly skilled and trusted dermatologist with over 30 years of practice in the field. As a board-certified dermatologist, Dr. DeSpain is dedicated to providing comprehensive medical, surgical, and cosmetic dermatology services to his patients. His commitment to understanding each patient’s unique needs and concerns sets him apart in this fast-paced world.

With a focus on patient-centered care, Dr. DeSpain believes in collaborating with his patients to create practical, safe, and effective treatment plans. He recognizes the importance of staying up to date with the latest advancements in dermatology and utilizes a wide range of treatment options to address various skin disorders.

Dr. DeSpain offers a comprehensive range of services:

  • Skin cancer detection and treatment
  • Treatment for acne, rosacea, psoriasis, eczema, rashes, warts, and more
  • Chronic and complex skin conditions
  • Skin rejuvenation treatments including Botox, filler, and removal of unwanted growths or moles

Having enjoyed weekends at the lake for over two decades, Dr. DeSpain is excited to call this area his home and be active in the community.

Osage Beach

5721 Osage Beach Parkway
Osage Beach, Missouri 65065
Tel:(573) 302-4696
BOOK APPOINTMENT
Especially in this fast-paced world, it is critical to take time to understand each patient’s unique needs and concerns. We have many options today to treat skin disorders, and we can work together to create a practical, safe, and effective care plan.
- John DeSpain, MD, FAAD
Google
5.0/5
• Forefront Dermatology
I was thoroughly impressed with the service I received from Dr. DeSpain. He and his assistant were very kind & knowledgeable. He answered all my questions & did not rush through my appointment.
Google
5.0/5
• Forefront Dermatology
Dr. DeSpain and staff are wonderful. He took great care of my Mother-in-law and was appropriately conservative in his choice of treatment. I highly recommend their clinic.
Google
5.0/5
• Forefront Dermatology
We were pleased with this office staff and the doctor. They were punctual, caring, very knowledgeable , and professional. We feel that we are well taken care of as we travel this road p
Google
5.0/5
• Forefront Dermatology
My provider took the time to listen and address all my 100 questions about my son’s condition and is diligently working to treat it. We are amazed at his knowledge and knew exactly what the issue was right away. We are so very pleased with your office, staff and everyone there treated us with the utmost respect. The office is very pleasant. We will definitely be back to follow up in three weeks. Thank you very much. Doctor DeSpain is the best!!!
Google
5.0/5
• Forefront Dermatology
Professional, explains clearly, cares, personable, and listens to my my symptoms.
Google
5.0/5
• Forefront Dermatology
Excellent timely care Very compassionate
Google
5.0/5
• Forefront Dermatology
Very professional! Takes time to explain everything we discussed. Highly recommend to anyone needing a dermatologist.
Google
5.0/5
• Forefront Dermatology
Dr DeSpain and staff are friendly, and very personable. They follow up on last years questions and help with suggestions on new ones. I would highly recommend them.
Google
5.0/5
• Forefront Dermatology
Always a pleasure to meet with Dr DeSpain. He’s very knowledgeable about my skin condition and always answers all my questions. A very considerate person
Google
5.0/5
• Forefront Dermatology
Finally a great experience with a doctor at the lake. I didn't feel rushed and he answered all my questions. He was kind and knowledgeable. Awesome experience!.
LOAD MORE REVIEWS
Education

Medical School:

University of Missouri – Columbia, MO

Dermatology Residency:

University of Missouri – Columbia, MO

Dermatopathology Fellowship:

University of Colorado – Denver, CO

Certificates
American Board of Dermatology
American Board of Dermatopathology
Professional Memberships
American Academy of Dermatology
Missouri Dermatologic Society
Missouri State Medical Association

*Age Restriction


For patients scheduling who are under 18 years of age (19 in Alabama) please make sure you have permission from your parent or legal guardian to schedule this appointment.  Your parent or legal guardian must accompany you on your initial visit and on certain subsequent visits to provide appropriate informed consent.
LOCATIONS
SERVICES