John DeSpain, MD, FAAD
Board-Certified Dermatologist
5.0 /5
292 reviews

John DeSpain, MD, FAAD

Dr. John DeSpain is a highly skilled and trusted dermatologist with over 30 years of practice in the field. As a board-certified dermatologist, Dr. DeSpain is dedicated to providing comprehensive medical, surgical, and cosmetic dermatology services to his patients. His commitment to understanding each patient’s unique needs and concerns sets him apart in this fast-paced world.

With a focus on patient-centered care, Dr. DeSpain believes in collaborating with his patients to create practical, safe, and effective treatment plans. He recognizes the importance of staying up to date with the latest advancements in dermatology and utilizes a wide range of treatment options to address various skin disorders.

Dr. DeSpain offers a comprehensive range of services:

  • Skin cancer detection and treatment
  • Treatment for acne, rosacea, psoriasis, eczema, rashes, warts, and more
  • Chronic and complex skin conditions
  • Skin rejuvenation treatments including Botox, filler, and removal of unwanted growths or moles

Having enjoyed weekends at the lake for over two decades, Dr. DeSpain is excited to call this area his home and be active in the community.

Osage Beach

5721 Osage Beach Parkway
Osage Beach, Missouri 65065
Tel:(573) 302-4696
BOOK APPOINTMENT
Especially in this fast-paced world, it is critical to take time to understand each patient’s unique needs and concerns. We have many options today to treat skin disorders, and we can work together to create a practical, safe, and effective care plan.
- John DeSpain, MD, FAAD
google
5.0/5
• Forefront Dermatology
Dr DeSpain was so helpful in taking care of my warts. He's always so pleasant in his interactions. His assistant Olivia was helpful as well today.
google
5.0/5
• Forefront Dermatology
Very friendly and noligable made me feel very relaxed and well taken care of
google
5.0/5
• Forefront Dermatology
Doctor DeSpain was friendly, personable, and easy to communicate with. Staff were also very friendly. Treatment plan was established quickly and thoroughly. Check in process was smooth and easy. We were in and out!
google
4.0/5
• Forefront Dermatology
Got all questions answered
google
5.0/5
• Forefront Dermatology
Dr. DeSpain is an amazing doctor who listens and cares. I would recommend him to anyone.
google
5.0/5
• Forefront Dermatology
Dr. DeSpain was great in diagnosing my poison ivy. He is so positive and pleasant whenever I go in for an appointment. The medication he prescribed has already taken effect and relieved the horrible itching.
google
5.0/5
• Forefront Dermatology
Dr. Despain is a Dr of the old school which is an EXCELLENT thing, & we are blessed to have a doctor of that caliber available to us in central Missouri! My husband and I both had contact with him today, & he is a jewel for sure! If you need a dermatologist, Dr. Despain is most definitely the caring person to look to for great care. His staff is a well chosen group of young people who pay attention to their patient's care as well. A great practice all the way around!
google
5.0/5
• Forefront Dermatology
Dr DeSpain, Dr Steen & Alex were very professional and kind. I felt they truly cared about making you feel comfortable and wanted to solve your concerns.
google
5.0/5
• Forefront Dermatology
Very detail oriented and explains his procedures. Thank you! See you next year.
google
5.0/5
• Forefront Dermatology
Excellent staff and Dr DeSpain always explains any procedure and does a wonderful job. Highly recommend
Education

Medical School:

University of Missouri – Columbia, MO

Dermatology Residency:

University of Missouri – Columbia, MO

Dermatopathology Fellowship:

University of Colorado – Denver, CO

Certificates
American Board of Dermatology
American Board of Dermatopathology
Professional Memberships
American Academy of Dermatology
Missouri Dermatologic Society
Missouri State Medical Association

*Age Restriction


For patients scheduling who are under 18 years of age (19 in Alabama) please make sure you have permission from your parent or legal guardian to schedule this appointment.  Your parent or legal guardian must accompany you on your initial visit and on certain subsequent visits to provide appropriate informed consent.
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